The SHI Lab

human B^act spliceosome

human catalytic step I spliceosome

yeast B spliceosome

yeast pre-B spliceosome

yeast post-catalytic spliceosome

yeast intron lariat spliceosome

human C* spliceosomal complex

yeast C^* spliceosome

yeast B^act spliceosome

yeast C complex spliceosome

yeast U4/U6.U5 tri-snRNP

S. pombe Spliceosome

Lsm1-7 Complex

Lsm Complex Bound to RNA

S. cerevisiae proteasome in M1 state

S. cerevisiae proteasome in M2 state

H. sapiens proteasome

H. sapiens proteasome bound to USP14-UbAl

MecA-ClpC

MecA Degradation Tag

Hausp Catalytic domain

Hausp/Ubal

TRAF-like domain of Hausp

Hausp

Hausp/p53

Hausp/MDM2

USP14

USP14/Ubal